Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

INTRODUCTION: Treatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited and CRE infections remain associated with high clinical failure and mortality rates, particularly in vulnerable patient populations. A Phase 3, multinational, open-label, randomized controlled tr...

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Pubblicato in:Infect Dis Ther
Autori principali: Wunderink, Richard G., Giamarellos-Bourboulis, Evangelos J., Rahav, Galia, Mathers, Amy J., Bassetti, Matteo, Vazquez, Jose, Cornely, Oliver A., Solomkin, Joseph, Bhowmick, Tanaya, Bishara, Jihad, Daikos, George L., Felton, Tim, Furst, Maria Jose Lopez, Kwak, Eun Jeong, Menichetti, Francesco, Oren, Ilana, Alexander, Elizabeth L., Griffith, David, Lomovskaya, Olga, Loutit, Jeffery, Zhang, Shu, Dudley, Michael N., Kaye, Keith S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Healthcare 2018
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249182/
https://ncbi.nlm.nih.gov/pubmed/30270406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40121-018-0214-1
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