Multifunctional, JNK-inhibiting nanotherapeutics for augmented elastic matrix regenerative repair in aortic aneurysms

Growth of abdominal aortic aneurysms (AAA), localized aortal wall expansions, is driven by the disruption and subsequent loss of aortal wall elastic fibers by matrix metalloproteases (MMPs). Since elastic fibers do not naturally regenerate or repair, arresting/reversing AAA growth has not been possi...

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Bibliografiska uppgifter
I publikationen:Drug Deliv Transl Res
Huvudupphovsmän: Camardo, Andrew, Seshadri, Dhruv, Broekelmann, Tom, Mecham, Robert, Ramamurthi, Anand
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837892/
https://ncbi.nlm.nih.gov/pubmed/28875468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0419-y
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