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Multifunctional Nanoparticles for Doxycycline Delivery Towards Localized Elastic Matrix Stabilization and Regenerative Repair

Abdominal aortic aneurysms (AAAs) are abnormal expansions of the aortic wall, typically characterized by chronic upregulation of matrix metalloproteases (MMPs) -2 and -9. These MMPs degrade elastin and elastic matrix within the aortic wall, leading to a progressive loss of elasticity of the abdomina...

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Bibliografske podrobnosti
Main Authors: Sivaraman, Balakrishnan, Ramamurthi, Anand
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622827/
https://ncbi.nlm.nih.gov/pubmed/23376127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.01.023
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