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Multifunctional Nanoparticles for Doxycycline Delivery Towards Localized Elastic Matrix Stabilization and Regenerative Repair

Abdominal aortic aneurysms (AAAs) are abnormal expansions of the aortic wall, typically characterized by chronic upregulation of matrix metalloproteases (MMPs) -2 and -9. These MMPs degrade elastin and elastic matrix within the aortic wall, leading to a progressive loss of elasticity of the abdomina...

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Main Authors: Sivaraman, Balakrishnan, Ramamurthi, Anand
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622827/
https://ncbi.nlm.nih.gov/pubmed/23376127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.01.023
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