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Multifunctional Nanoparticles for Doxycycline Delivery Towards Localized Elastic Matrix Stabilization and Regenerative Repair

Abdominal aortic aneurysms (AAAs) are abnormal expansions of the aortic wall, typically characterized by chronic upregulation of matrix metalloproteases (MMPs) -2 and -9. These MMPs degrade elastin and elastic matrix within the aortic wall, leading to a progressive loss of elasticity of the abdomina...

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Détails bibliographiques
Auteurs principaux: Sivaraman, Balakrishnan, Ramamurthi, Anand
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622827/
https://ncbi.nlm.nih.gov/pubmed/23376127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.01.023
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