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Cathepsin K-Targeted Sub-Micron Particles for Regenerative Repair of Vascular Elastic Matrix

Abdominal Aortic Aneurysms (AAA) involve slow dilation and weakening of the aortic wall due to breakdown of structural matrix components, such as elastic fibers by chronically overexpressed matrix metalloproteinases (MMPs), primarily, MMPs-2 and −9. Auto-regenerative repair of disrupted elastic fibe...

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Foilsithe in:Acta Biomater
Main Authors: Jennewine, Brenton, Fox, Jonathan, Ramamurthi, Anand
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361138/
https://ncbi.nlm.nih.gov/pubmed/28087488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.01.032
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