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Cathepsin K-Targeted Sub-Micron Particles for Regenerative Repair of Vascular Elastic Matrix

Abdominal Aortic Aneurysms (AAA) involve slow dilation and weakening of the aortic wall due to breakdown of structural matrix components, such as elastic fibers by chronically overexpressed matrix metalloproteinases (MMPs), primarily, MMPs-2 and −9. Auto-regenerative repair of disrupted elastic fibe...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Jennewine, Brenton, Fox, Jonathan, Ramamurthi, Anand
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361138/
https://ncbi.nlm.nih.gov/pubmed/28087488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.01.032
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