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Multifunctional, JNK-inhibiting nanotherapeutics for augmented elastic matrix regenerative repair in aortic aneurysms

Growth of abdominal aortic aneurysms (AAA), localized aortal wall expansions, is driven by the disruption and subsequent loss of aortal wall elastic fibers by matrix metalloproteases (MMPs). Since elastic fibers do not naturally regenerate or repair, arresting/reversing AAA growth has not been possi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Deliv Transl Res
मुख्य लेखकों: Camardo, Andrew, Seshadri, Dhruv, Broekelmann, Tom, Mecham, Robert, Ramamurthi, Anand
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837892/
https://ncbi.nlm.nih.gov/pubmed/28875468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0419-y
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