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From the Cover: ROS-Induced Store-Operated Ca(2+) Entry Coupled to PARP-1 Hyperactivation Is Independent of PARG Activity in Necrotic Cell Death
2,3,5-tris(Glutathion-S-yl)hydroquinone, a potent nephrotoxic and nephrocarcinogenic metabolite of benzene and hydroquinone, generates reactive oxygen species (ROS) causing DNA strand breaks and the subsequent activation of DNA repair enzymes, including poly(ADP-ribose) polymerase (PARP)-1. Under ro...
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| Publicado no: | Toxicol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837598/ https://ncbi.nlm.nih.gov/pubmed/28525621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx106 |
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