A Dual Role for Poly(ADP-Ribose) Polymerase-1 
During Caspase-Dependent Apoptosis

2,3,5-Tris(glutathion-S-yl)hydroquinone (TGHQ), a metabolite of benzene, catalyzes the generation of reactive oxygen species (ROS) and caspase-dependent apoptosis in human promyelocytic leukemia (HL-60) cells. We now report that TGHQ induces severe DNA damage, as evidenced by DNA ladder formation an...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Zhang, Fengjiao, Lau, Serrine S., Monks, Terrence J.
Format: Artigo
Jezik:Inglês
Izdano: OUP 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491962/
https://ncbi.nlm.nih.gov/pubmed/22523229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs142
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki