Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9

Mouse artificial chromosome (MAC) vectors have several advantages as gene delivery vectors, such as stable and independent maintenance in host cells without integration, transferability from donor cells to recipient cells via microcell-mediated chromosome transfer (MMCT), and the potential for loadi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Honma, Kazuhisa, Abe, Satoshi, Endo, Takeshi, Uno, Narumi, Oshimura, Mitsuo, Ohbayashi, Tetsuya, Kazuki, Yasuhiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837097/
https://ncbi.nlm.nih.gov/pubmed/29505588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193642
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