Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9

Mouse artificial chromosome (MAC) vectors have several advantages as gene delivery vectors, such as stable and independent maintenance in host cells without integration, transferability from donor cells to recipient cells via microcell-mediated chromosome transfer (MMCT), and the potential for loadi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Honma, Kazuhisa, Abe, Satoshi, Endo, Takeshi, Uno, Narumi, Oshimura, Mitsuo, Ohbayashi, Tetsuya, Kazuki, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837097/
https://ncbi.nlm.nih.gov/pubmed/29505588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193642
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