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Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP

The stringent response is a global reprogramming of bacterial physiology that renders cells more tolerant to antibiotics and induces virulence gene expression in pathogens in response to stress. This process is driven by accumulation of the intracellular alarmone guanosine-5′-di(tri)phosphate-3′-dip...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Manav, Melek Cemre, Beljantseva, Jelena, Bojer, Martin S., Tenson, Tanel, Ingmer, Hanne, Hauryliuk, Vasili, Brodersen, Ditlev E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836137/
https://ncbi.nlm.nih.gov/pubmed/29326162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001374
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