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The RelA/SpoT Homolog (RSH) Superfamily: Distribution and Functional Evolution of ppGpp Synthetases and Hydrolases across the Tree of Life

RelA/SpoT Homologue (RSH) proteins, named for their sequence similarity to the RelA and SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize and/or hydrolyze the alarmone ppGpp, activator of the “stringent” response and regulator of cellular metabolism. The classical “...

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Detalhes bibliográficos
Main Authors: Atkinson, Gemma C., Tenson, Tanel, Hauryliuk, Vasili
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153485/
https://ncbi.nlm.nih.gov/pubmed/21858139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023479
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