Regulation of the opposing (p)ppGpp synthetase and hydrolase activities in a bifunctional RelA/SpoT homologue from Staphylococcus aureus

The stringent response is characterized by (p)ppGpp synthesis resulting in repression of translation and reprogramming of the transcriptome. In Staphylococcus aureus, (p)ppGpp is synthesized by the long RSH (RelA/SpoT homolog) enzyme, Rel(Sau) or by one of the two short synthetases (RelP, RelQ). RSH...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Gratani, Fabio Lino, Horvatek, Petra, Geiger, Tobias, Borisova, Marina, Mayer, Christoph, Grin, Iwan, Wagner, Samuel, Steinchen, Wieland, Bange, Gert, Velic, Ana, Maček, Boris, Wolz, Christiane
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053245/
https://ncbi.nlm.nih.gov/pubmed/29985927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007514
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