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Role of the (p)ppGpp Synthase RSH, a RelA/SpoT Homolog, in Stringent Response and Virulence of Staphylococcus aureus

In most bacteria, nutrient limitations provoke the stringent control through the rapid synthesis of the alarmones pppGpp and ppGpp. Little is known about the stringent control in the human pathogen Staphylococcus aureus, partly due to the essentiality of the major (p)ppGpp synthase/hydrolase enzyme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Geiger, Tobias, Goerke, Christiane, Fritz, Michaela, Schäfer, Tina, Ohlsen, Knut, Liebeke, Manuel, Lalk, Michael, Wolz, Christiane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863498/
https://ncbi.nlm.nih.gov/pubmed/20212088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01439-09
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