Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ

The nutritional alarmones ppGpp and pppGpp (collectively: (p)ppGpp) are nucleotide-based second messengers enabling bacteria to respond to environmental and stress conditions. Several bacterial species contain two highly homologous (p)ppGpp synthetases named RelP (SAS2, YwaC) and RelQ (SAS1, YjbM)....

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Udgivet i:Sci Rep
Main Authors: Steinchen, Wieland, Vogt, Marian S., Altegoer, Florian, Giammarinaro, Pietro I., Horvatek, Petra, Wolz, Christiane, Bange, Gert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794853/
https://ncbi.nlm.nih.gov/pubmed/29391580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20634-4
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