Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone

Nucleotide-based second messengers serve in the response of living organisms to environmental changes. In bacteria and plant chloroplasts, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) [collectively named “(p)ppGpp”] act as alarmones that globally reprogram cellular physiolo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Steinchen, Wieland, Schuhmacher, Jan S., Altegoer, Florian, Fage, Christopher D., Srinivasan, Vasundara, Linne, Uwe, Marahiel, Mohamed A., Bange, Gert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629338/
https://ncbi.nlm.nih.gov/pubmed/26460002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505271112
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