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Loss of mitochondrial protease ClpP protects mice from diet‐induced obesity and insulin resistance

Caseinolytic peptidase P (ClpP) is a mammalian quality control protease that is proposed to play an important role in the initiation of the mitochondrial unfolded protein response (UPR (mt)), a retrograde signaling response that helps to maintain mitochondrial protein homeostasis. Mitochondrial dysf...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Bhaskaran, Shylesh, Pharaoh, Gavin, Ranjit, Rojina, Murphy, Ashley, Matsuzaki, Satoshi, Nair, Binoj C, Forbes, Brittany, Gispert, Suzana, Auburger, Georg, Humphries, Kenneth M, Kinter, Michael, Griffin, Timothy M, Deepa, Sathyaseelan S
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836096/
https://ncbi.nlm.nih.gov/pubmed/29420235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745009
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