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Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

Human β‐cells are functionally mature by the age of 1 year. The timeline and mechanisms of this maturation are unknown owing to the exceptional availability of testable tissue. Here, we report the first in vitro study of insulin secretion by islets from a 5‐day‐old newborn. Glucose was inefficient a...

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Dades bibliogràfiques
Publicat a:J Diabetes Investig
Autors principals: Henquin, Jean‐Claude, Nenquin, Myriam
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835448/
https://ncbi.nlm.nih.gov/pubmed/28597607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12701
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