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Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?
BACKGROUND: Diabetes always involves variable degrees of β-cell demise and malfunction leading to insufficient insulin secretion. Besides clinical investigations, many research projects used rodent islets to study various facets of β-cell pathophysiology. Their important contributions laid the found...
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| Veröffentlicht in: | Mol Metab |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8065218/ https://ncbi.nlm.nih.gov/pubmed/33737253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101212 |
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