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Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

Human β‐cells are functionally mature by the age of 1 year. The timeline and mechanisms of this maturation are unknown owing to the exceptional availability of testable tissue. Here, we report the first in vitro study of insulin secretion by islets from a 5‐day‐old newborn. Glucose was inefficient a...

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Detalhes bibliográficos
Publicado no:J Diabetes Investig
Main Authors: Henquin, Jean‐Claude, Nenquin, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835448/
https://ncbi.nlm.nih.gov/pubmed/28597607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12701
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