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Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

Human β‐cells are functionally mature by the age of 1 year. The timeline and mechanisms of this maturation are unknown owing to the exceptional availability of testable tissue. Here, we report the first in vitro study of insulin secretion by islets from a 5‐day‐old newborn. Glucose was inefficient a...

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Detaylı Bibliyografya
Yayımlandı:J Diabetes Investig
Asıl Yazarlar: Henquin, Jean‐Claude, Nenquin, Myriam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835448/
https://ncbi.nlm.nih.gov/pubmed/28597607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12701
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