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Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding

The epidermal growth factor receptor (EGFR) is an important transmembrane glycoprotein kinase involved the initiation or perpetuation of signal transduction cascades within cells. These processes occur after EGFR binds to a ligand [epidermal growth factor (EGF)], thus inducing its dimerization and t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proteins
मुख्य लेखकों: Taylor, Eric S., Pol-Fachin, Laercio, Lins, Roberto D., Lower, Steven K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835389/
https://ncbi.nlm.nih.gov/pubmed/28019699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25220
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