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Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding

The epidermal growth factor receptor (EGFR) is an important transmembrane glycoprotein kinase involved the initiation or perpetuation of signal transduction cascades within cells. These processes occur after EGFR binds to a ligand [epidermal growth factor (EGF)], thus inducing its dimerization and t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proteins
Päätekijät: Taylor, Eric S., Pol-Fachin, Laercio, Lins, Roberto D., Lower, Steven K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835389/
https://ncbi.nlm.nih.gov/pubmed/28019699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25220
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