Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR

Cystic Fibrosis (CF) due to the ΔF508 mutation of cystic fibrosis transmembrane conductance regulator (CFTR) can be treated with a combination of cysteamine and Epigallocatechin gallate (EGCG). Since ECGC is not a clinically approved drug, we attempted to identify other compounds that might favourab...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zhang, Shaoyi, Stoll, Gautier, Pedro, José Manuel Bravo San, Sica, Valentina, Sauvat, Allan, Obrist, Florine, Kepp, Oliver, Li, Yousheng, Maiuri, Luigi, Zamzami, Naoufal, Kroemer, Guido
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833759/
https://ncbi.nlm.nih.gov/pubmed/29415993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0235-9
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