Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR

Cystic Fibrosis (CF) due to the ΔF508 mutation of cystic fibrosis transmembrane conductance regulator (CFTR) can be treated with a combination of cysteamine and Epigallocatechin gallate (EGCG). Since ECGC is not a clinically approved drug, we attempted to identify other compounds that might favourab...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Shaoyi, Stoll, Gautier, Pedro, José Manuel Bravo San, Sica, Valentina, Sauvat, Allan, Obrist, Florine, Kepp, Oliver, Li, Yousheng, Maiuri, Luigi, Zamzami, Naoufal, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833759/
https://ncbi.nlm.nih.gov/pubmed/29415993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0235-9
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