PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

Somatic activating mutations within the PIK3CA gene have been recently detected in sporadic lymphatic and venous malformations, and in vascular malformations (VM) associated to overgrowth syndromes, such as CLOVES and Klippel–Trenaunay syndrome. Although VM are often limited to specific tissue areas...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: di Blasio, Laura, Puliafito, Alberto, Gagliardi, Paolo Armando, Comunanza, Valentina, Somale, Desiana, Chiaverina, Giulia, Bussolino, Federico, Primo, Luca
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833448/
https://ncbi.nlm.nih.gov/pubmed/29352118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0064-x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares