Suboptimal extracellular pH values alter DNA damage response to induced double‐strand breaks

Conditions leading to unrepaired DNA double‐stranded breaks are potent inducers of genetic instability. Systemic conditions may lead to fluctuation of hydrogen ions in the cellular microenvironment, and we show that small variations in extracellular pH, termed suboptimal pHe, can decrease the effici...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Open Bio
Prif Awduron: Massonneau, Julien, Ouellet, Camille, Lucien, Fabrice, Dubois, Claire M., Tyler, Jessica, Boissonneault, Guylain
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832969/
https://ncbi.nlm.nih.gov/pubmed/29511618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12384
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