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Epigenetic Modifications in Double Strand Break DNA Damage Signaling and Repair

Factors involved in the cellular response to double strand break (DSB) DNA damage have been identified as potential therapeutic targets that would greatly sensitize cancer cells to radiotherapy and genotoxic chemotherapy. They could disable the repair machinery and/or reinstate normal cell cycle che...

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Détails bibliographiques
Auteurs principaux: Rossetto, Dorine, Truman, Andrew W., Kron, Stephen J., Côté, Jacques
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940951/
https://ncbi.nlm.nih.gov/pubmed/20823147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0513
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