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Epigenetic Modifications in Double Strand Break DNA Damage Signaling and Repair

Factors involved in the cellular response to double strand break (DSB) DNA damage have been identified as potential therapeutic targets that would greatly sensitize cancer cells to radiotherapy and genotoxic chemotherapy. They could disable the repair machinery and/or reinstate normal cell cycle che...

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Detalhes bibliográficos
Main Authors: Rossetto, Dorine, Truman, Andrew W., Kron, Stephen J., Côté, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940951/
https://ncbi.nlm.nih.gov/pubmed/20823147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0513
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