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DNA damage signaling in response to double-strand breaks during mitosis
The signaling cascade initiated in response to DNA double-strand breaks (DSBs) has been extensively investigated in interphase cells. Here, we show that mitotic cells treated with DSB-inducing agents activate a “primary” DNA damage response (DDR) comprised of early signaling events, including activa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930281/ https://ncbi.nlm.nih.gov/pubmed/20660628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911156 |
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