Epigenetic Mechanisms in DNA Double Strand Break Repair: A Clinical Review

Upon the induction of DNA damage, the chromatin structure unwinds to allow access to enzymes to catalyse the repair. The regulation of the winding and unwinding of chromatin occurs via epigenetic modifications, which can alter gene expression without changing the DNA sequence. Epigenetic mechanisms...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Fernandez, Alejandra, O’Leary, Connor, O’Byrne, Kenneth J, Burgess, Joshua, Richard, Derek J, Suraweera, Amila
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292790/
https://ncbi.nlm.nih.gov/pubmed/34307454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.685440
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