Epigenetic Mechanisms in DNA Double Strand Break Repair: A Clinical Review

Upon the induction of DNA damage, the chromatin structure unwinds to allow access to enzymes to catalyse the repair. The regulation of the winding and unwinding of chromatin occurs via epigenetic modifications, which can alter gene expression without changing the DNA sequence. Epigenetic mechanisms...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Fernandez, Alejandra, O’Leary, Connor, O’Byrne, Kenneth J, Burgess, Joshua, Richard, Derek J, Suraweera, Amila
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292790/
https://ncbi.nlm.nih.gov/pubmed/34307454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.685440
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