Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

DNA repair pathways are essential to maintain the integrity of the genome and prevent cell death and tumourigenesis. Here, we show that the Barrier-to-Autointegration Factor (Banf1) protein has a role in the repair of DNA double-strand breaks. Banf1 is characterized as a nuclear envelope protein and...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Burgess, Joshua T, Cheong, Chee Man, Suraweera, Amila, Sobanski, Thais, Beard, Sam, Dave, Keyur, Rose, Maddison, Boucher, Didier, Croft, Laura V, Adams, Mark N, O’Byrne, Kenneth, Richard, Derek J, Bolderson, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034644/
https://ncbi.nlm.nih.gov/pubmed/33660778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab110
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