Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

DNA repair pathways are essential to maintain the integrity of the genome and prevent cell death and tumourigenesis. Here, we show that the Barrier-to-Autointegration Factor (Banf1) protein has a role in the repair of DNA double-strand breaks. Banf1 is characterized as a nuclear envelope protein and...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Burgess, Joshua T, Cheong, Chee Man, Suraweera, Amila, Sobanski, Thais, Beard, Sam, Dave, Keyur, Rose, Maddison, Boucher, Didier, Croft, Laura V, Adams, Mark N, O’Byrne, Kenneth, Richard, Derek J, Bolderson, Emma
格式: Artigo
語言:Inglês
出版: Oxford University Press 2021
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034644/
https://ncbi.nlm.nih.gov/pubmed/33660778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab110
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