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Epigenetic Modifications in Double Strand Break DNA Damage Signaling and Repair

Factors involved in the cellular response to double strand break (DSB) DNA damage have been identified as potential therapeutic targets that would greatly sensitize cancer cells to radiotherapy and genotoxic chemotherapy. They could disable the repair machinery and/or reinstate normal cell cycle che...

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Bibliografiske detaljer
Main Authors: Rossetto, Dorine, Truman, Andrew W., Kron, Stephen J., Côté, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940951/
https://ncbi.nlm.nih.gov/pubmed/20823147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0513
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