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Suboptimal extracellular pH values alter DNA damage response to induced double‐strand breaks

Conditions leading to unrepaired DNA double‐stranded breaks are potent inducers of genetic instability. Systemic conditions may lead to fluctuation of hydrogen ions in the cellular microenvironment, and we show that small variations in extracellular pH, termed suboptimal pHe, can decrease the effici...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Massonneau, Julien, Ouellet, Camille, Lucien, Fabrice, Dubois, Claire M., Tyler, Jessica, Boissonneault, Guylain
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832969/
https://ncbi.nlm.nih.gov/pubmed/29511618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12384
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