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Suboptimal extracellular pH values alter DNA damage response to induced double‐strand breaks

Conditions leading to unrepaired DNA double‐stranded breaks are potent inducers of genetic instability. Systemic conditions may lead to fluctuation of hydrogen ions in the cellular microenvironment, and we show that small variations in extracellular pH, termed suboptimal pHe, can decrease the effici...

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Detalles Bibliográficos
Publicado en:FEBS Open Bio
Main Authors: Massonneau, Julien, Ouellet, Camille, Lucien, Fabrice, Dubois, Claire M., Tyler, Jessica, Boissonneault, Guylain
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832969/
https://ncbi.nlm.nih.gov/pubmed/29511618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12384
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