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Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells

Most DNA double-strand breaks (DSBs) formed in a natural environment have chemical modifications at or near the ends that preclude direct religation and require removal or other processing so that rejoining can proceed. Free radical-mediated DSBs typically bear unligatable 3′-phosphate or 3′-phospho...

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Autor principal: Povirk, Lawrence F.
Format: Artigo
Idioma:Inglês
Publicat: International Scholarly Research Network 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825254/
https://ncbi.nlm.nih.gov/pubmed/24236237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/345805
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