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Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy

There is abundant evidence for formation of G protein-coupled receptor heteromers in heterologous expression systems, but little is known of the function of heteromers in native systems. Heteromers of δ and κ opioid receptors (DOR-KOR heteromers) have been identified in native systems. We previously...

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Detalles Bibliográficos
Publicado en:Mol Pharmacol
Main Authors: Jacobs, Blaine A., Pando, Miryam M., Jennings, Elaine, Chavera, Teresa A., Clarke, William P., Berg, Kelly A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832326/
https://ncbi.nlm.nih.gov/pubmed/29436492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109975
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