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Golgi Associated HIF1a Serves as a Reserve in Melanoma Cells
Hypoxia-inducible factor-1alpha (HIF1a) is a key transcriptional regulator that enables cellular metabolic adaptation to low levels of oxygen. Multiple mechanisms, including lysosomal degradation, control the levels of HIF1a protein. Here we show that HIF1a protein degradation is resistant to lysoso...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831122/ https://ncbi.nlm.nih.gov/pubmed/26375488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25381 |
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