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PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy

Posttranslational modifications of p53 integrate diverse stress signals and regulate its activity, but their combinatorial contribution to overall p53 function is not clear. We investigated the roles of lysine (K) acetylation and sumoylation on p53 and their relation to apoptosis and autophagy. Here...

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Detaylı Bibliyografya
Asıl Yazarlar: Naidu, Samisubbu R., Lakhter, Alexander J., Androphy, Elliot J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409012/
https://ncbi.nlm.nih.gov/pubmed/22751435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21091
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