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PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy

Posttranslational modifications of p53 integrate diverse stress signals and regulate its activity, but their combinatorial contribution to overall p53 function is not clear. We investigated the roles of lysine (K) acetylation and sumoylation on p53 and their relation to apoptosis and autophagy. Here...

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Detalhes bibliográficos
Main Authors: Naidu, Samisubbu R., Lakhter, Alexander J., Androphy, Elliot J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409012/
https://ncbi.nlm.nih.gov/pubmed/22751435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21091
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