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Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth

Tumors rely on multiple nutrients to meet cellular bioenergetics and macromolecular synthesis demands of rapidly dividing cells. Although the role of glucose and glutamine in cancer metabolism is well understood, the relative contribution of acetate metabolism remains to be clarified. We show that g...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lakhter, Alexander J., Hamilton, James, Konger, Raymond L., Brustovetsky, Nickolay, Broxmeyer, Hal E., Naidu, Samisubbu R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063972/
https://ncbi.nlm.nih.gov/pubmed/27539851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712166
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