Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth

Tumors rely on multiple nutrients to meet cellular bioenergetics and macromolecular synthesis demands of rapidly dividing cells. Although the role of glucose and glutamine in cancer metabolism is well understood, the relative contribution of acetate metabolism remains to be clarified. We show that g...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Lakhter, Alexander J., Hamilton, James, Konger, Raymond L., Brustovetsky, Nickolay, Broxmeyer, Hal E., Naidu, Samisubbu R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063972/
https://ncbi.nlm.nih.gov/pubmed/27539851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712166
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