Učitavanje...
Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity
HIV-1 broadly neutralizing antibodies (bNAbs) are being explored as passively administered therapeutic and preventative agents. However, the extensively diversified HIV-1 envelope glycoproteins (Env) rapidly acquire mutations to evade individual bNAbs in monotherapy regimens. The use of a “single” a...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830440/ https://ncbi.nlm.nih.gov/pubmed/29491415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03335-4 |
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