HIV-1 gp120-CD4i Antibody Complex Elicits CD4 Binding Site Specific Antibody Response in Mice

Elicitation of broadly neutralizing antibody (bNAb) responses toward the conserved HIV-1 Envelope (Env) CD4 binding site (CD4bs) by vaccination is an important goal for vaccine development and yet to be achieved. The outcome of previous immunogenicity studies suggests that the limited accessibility...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Galkin, Andrey, Chen, Yajing, Guenaga, Javier, O’Dell, Sijy, Acevedo, Roderico, Steinhardt, James J., Wang, Yimeng, Wilson, Richard, Chiang, Chi-I, Doria-Rose, Nicole, Grishaev, Alexander V., Mascola, John R., Li, Yuxing
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065964/
https://ncbi.nlm.nih.gov/pubmed/32066595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901051
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