HIV-1 gp120-CD4i Antibody Complex Elicits CD4 Binding Site Specific Antibody Response in Mice

Elicitation of broadly neutralizing antibody (bNAb) responses toward the conserved HIV-1 Envelope (Env) CD4 binding site (CD4bs) by vaccination is an important goal for vaccine development and yet to be achieved. The outcome of previous immunogenicity studies suggests that the limited accessibility...

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發表在:J Immunol
Main Authors: Galkin, Andrey, Chen, Yajing, Guenaga, Javier, O’Dell, Sijy, Acevedo, Roderico, Steinhardt, James J., Wang, Yimeng, Wilson, Richard, Chiang, Chi-I, Doria-Rose, Nicole, Grishaev, Alexander V., Mascola, John R., Li, Yuxing
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065964/
https://ncbi.nlm.nih.gov/pubmed/32066595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901051
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