Steady-State Clozapine and Norclozapine Pharmacokinetics in Maori and European Patients

BACKGROUND: Clozapine is the most effective drug for treatment-resistant schizophrenia, but its use is limited by toxicity. Because ethnicity has been reported to affect clozapine metabolism, we compared its steady state pharmacokinetics in New Zealand Maori and European patients. METHODS: Clozapine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EBioMedicine
Egile Nagusiak: Menkes, David B., Glue, Paul, Gale, Christopher, Lam, Frederic, Hung, Cheung-Tak, Hung, Noelyn
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828556/
https://ncbi.nlm.nih.gov/pubmed/29254680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.11.030
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