Efficient farnesylation of an extended C-terminal C(x)(3)X sequence motif expands the scope of the prenylated proteome

Protein prenylation is a post-translational modification that has been most commonly associated with enabling protein trafficking to and interaction with cellular membranes. In this process, an isoprenoid group is attached to a cysteine near the C terminus of a substrate protein by protein farnesylt...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Blanden, Melanie J., Suazo, Kiall F., Hildebrandt, Emily R., Hardgrove, Daniel S., Patel, Meet, Saunders, William P., Distefano, Mark D., Schmidt, Walter K., Hougland, James L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827447/
https://ncbi.nlm.nih.gov/pubmed/29282289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805770
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