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Isoprenoids and Protein Prenylation: Implications in the Pathogenesis and Therapeutic Intervention of Alzheimer’s Disease

The mevalonate-isoprenoid-cholesterol biosynthesis pathway plays a key role in human health and disease. The importance of this pathway is underscored by the discovery that two major isoprenoids, farnesyl and geranylgeranyl pyrophosphate, are required to modify an array of proteins through a process...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Jeong, Angela, Suazo, Kiall Francis, Wood, W. Gibson, Distefano, Mark D., Li, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101676/
https://ncbi.nlm.nih.gov/pubmed/29718780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458070
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