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Isoprenoids and Protein Prenylation: Implications in the Pathogenesis and Therapeutic Intervention of Alzheimer’s Disease

The mevalonate-isoprenoid-cholesterol biosynthesis pathway plays a key role in human health and disease. The importance of this pathway is underscored by the discovery that two major isoprenoids, farnesyl and geranylgeranyl pyrophosphate, are required to modify an array of proteins through a process...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Crit Rev Biochem Mol Biol
Prif Awduron: Jeong, Angela, Suazo, Kiall Francis, Wood, W. Gibson, Distefano, Mark D., Li, Ling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101676/
https://ncbi.nlm.nih.gov/pubmed/29718780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458070
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