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Isoprenoids and Protein Prenylation: Implications in the Pathogenesis and Therapeutic Intervention of Alzheimer’s Disease

The mevalonate-isoprenoid-cholesterol biosynthesis pathway plays a key role in human health and disease. The importance of this pathway is underscored by the discovery that two major isoprenoids, farnesyl and geranylgeranyl pyrophosphate, are required to modify an array of proteins through a process...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Crit Rev Biochem Mol Biol
Main Authors: Jeong, Angela, Suazo, Kiall Francis, Wood, W. Gibson, Distefano, Mark D., Li, Ling
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101676/
https://ncbi.nlm.nih.gov/pubmed/29718780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458070
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