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Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue

Severe malaria due to Plasmodium falciparum infection remains a serious threat to health worldwide and new therapeutic targets are highly desirable. Small molecule inhibitors of prenyl transferases, enzymes that catalyze the post-translational isoprenyl modifications of proteins, exhibit potent anti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Suazo, Kiall F., Schaber, Chad, Palsuledesai, Charuta C., Odom John, Audrey R., Distefano, Mark D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141570/
https://ncbi.nlm.nih.gov/pubmed/27924931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38615
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