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Isoprenoids and Protein Prenylation: Implications in the Pathogenesis and Therapeutic Intervention of Alzheimer’s Disease

The mevalonate-isoprenoid-cholesterol biosynthesis pathway plays a key role in human health and disease. The importance of this pathway is underscored by the discovery that two major isoprenoids, farnesyl and geranylgeranyl pyrophosphate, are required to modify an array of proteins through a process...

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Bibliografiska uppgifter
I publikationen:Crit Rev Biochem Mol Biol
Huvudupphovsmän: Jeong, Angela, Suazo, Kiall Francis, Wood, W. Gibson, Distefano, Mark D., Li, Ling
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101676/
https://ncbi.nlm.nih.gov/pubmed/29718780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458070
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