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Sickle Cell Imaging Flow Cytometry Assay (SIFCA)

Hemoglobin S polymerization under hypoxic conditions in sickle cell disorders causes characteristic shape changes to human red blood cells. Previous sickling assays used to investigate the efficacy of novel agents to treat these disorders are laborious and observer dependent. Here, we describe a par...

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Bibliografiska uppgifter
I publikationen:Methods Mol Biol
Huvudupphovsmän: Fertrin, Kleber Y., Samsel, Leigh, van Beers, Eduard J., Mendelsohn, Laurel, Kato, Gregory J., McCoy, J. Philip
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826554/
https://ncbi.nlm.nih.gov/pubmed/27460253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3302-0_20
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