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Sickle Cell Imaging Flow Cytometry Assay (SIFCA)

Hemoglobin S polymerization under hypoxic conditions in sickle cell disorders causes characteristic shape changes to human red blood cells. Previous sickling assays used to investigate the efficacy of novel agents to treat these disorders are laborious and observer dependent. Here, we describe a par...

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Dades bibliogràfiques
Publicat a:Methods Mol Biol
Autors principals: Fertrin, Kleber Y., Samsel, Leigh, van Beers, Eduard J., Mendelsohn, Laurel, Kato, Gregory J., McCoy, J. Philip
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826554/
https://ncbi.nlm.nih.gov/pubmed/27460253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3302-0_20
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