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Sickle Cell Imaging Flow Cytometry Assay (SIFCA)

Hemoglobin S polymerization under hypoxic conditions in sickle cell disorders causes characteristic shape changes to human red blood cells. Previous sickling assays used to investigate the efficacy of novel agents to treat these disorders are laborious and observer dependent. Here, we describe a par...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Fertrin, Kleber Y., Samsel, Leigh, van Beers, Eduard J., Mendelsohn, Laurel, Kato, Gregory J., McCoy, J. Philip
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826554/
https://ncbi.nlm.nih.gov/pubmed/27460253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3302-0_20
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